Cytotoxic effects of White-MTA and MTA-Bio cements on odontoblast-like cells (MDPC-23)

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Cytotoxic effects of White-MTA and MTA-Bio cements on odontoblast-like cells (MDPC-23).

This study evaluated the cytotoxic effects of 2 mineral trioxide aggregate (MTA) cements - White-MTA-Angelus and a new formulation, MTA-Bio - on odontoblast-like cell (MDPC-23) cultures. Twenty-four disc-shaped (2 mm diameter x 2 mm thick) specimens were fabricated from each material and immersed individually in wells containing 1 mL of DMEM culture medium for either 24 h or 7 days to obtain ex...

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Study of two MTA cements

INTRODUCTION To determine and compare the pH, conductivity and calcium release of an experimental Portland cement (PE) consisting of trioxid mineral aggregate and a comercially available modified Portland cement (C.P.M.) after 1, 2, 3, 4, 8, 10, 15 and 30 days. MATERIAL AND METHODS Cements were mixed following the manufacturer's instructions, with a powder: liquid ratio of 3:1. Each cement wa...

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Protective Effect of Sodium Ascorbate on MDPC-23 Odontoblast-Like Cells Exposed to a Bleaching Agent

OBJECTIVES To evaluate the cytotoxic effects of a bleaching agent composed of 0.01% carbamide peroxide (CP; 2.21mug/ml H(2)O(2)) on the MDPC-23 odontoblastic cell line, and to determine whether sodium ascorbate (SA) is capable of reducing, or even eliminating, the toxic effects caused by this bleaching agent. METHODS The cells were seeded in wells and incubated for 48 hours. CP and SA were di...

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In vitro biocompatibility and oxidative stress profiles of different hydraulic calcium silicate cements.

INTRODUCTION MTA Plus is a new calcium silicate cement with unknown cytotoxicity characteristics. The objectives of this study were to examine the effect of MTA Plus on the viability, apoptosis/necrosis profile, and oxidative stress levels of rat odontoblast-like cells. METHODS MDPC-23 cells were exposed to gray and white MTA Plus (GMTAP, WMTAP), gray and white ProRoot MTA (GMTA, WMTA) cement...

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ژورنال

عنوان ژورنال: Brazilian Dental Journal

سال: 2010

ISSN: 0103-6440

DOI: 10.1590/s0103-64402010000100004